The Noida International Institute of Medical Sciences (NIIMS), Gautam Budh Nagar, has successfully managed a rare and complex case of Banti’s Syndrome in a 30-year-old male patient. This remarkable case underlines the importance of early diagnosis and targeted treatment in improving the quality of life for individuals with this rare disorder.
Clinical Condition & Issues
Dr. Sumol Ratna, Assistant Professor, Department of General Medicine, led the multidisciplinary team managing the case. The patient was admitted with recurrent episodes of hematemesis (vomiting of blood) persisting for 15 days. Additional symptoms included fever, bloating, abdominal distension, and general weakness. The patient had a history of multiple hospitalizations over the last five years without a definitive diagnosis or substantial improvement.
Diagnostic Investigations
The patient underwent comprehensive investigations, including:
- Blood tests indicating hypersplenism.
- Ultrasonography, revealing splenomegaly.
- Upper GI Endoscopy, which ruled out cirrhotic causes of portal hypertension.
Based on clinical and investigative findings, the patient was diagnosed with Banti’s Syndrome (Non-Cirrhotic Portal Fibrosis, NCPF), a rare form of Chronic Liver Disease (Child A).
Management and Outcome
The treatment plan included:
- Multiple blood transfusions to address severe anemia.
- Propranolol (40 mg) to reduce portal pressures.
- Diuretics and other supportive therapies to alleviate symptoms.
Following treatment, the patient showed significant hemodynamic improvement, regained the ability to perform daily activities, and was discharged on a minimal medication regimen. He continues to receive regular follow-up care at NIIMS Medical College & Hospital.
Banti’s Syndrome: A Rare Diagnosis
Banti’s Syndrome is a diagnosis of exclusion, requiring meticulous investigation to rule out other causes of portal hypertension, splenomegaly, and anemia. Early intervention and proper management can lead to remarkable patient outcomes.
According to Dr. Sumol Ratna, “This case underscores the need to keep Banti’s Syndrome in mind, particularly in young patients presenting with hypersplenism and recurrent gastrointestinal bleeding. Early diagnosis and targeted treatment are crucial for recovery and long-term management.”
NIIMS remains committed to providing advanced, patient-centric care and contributing to medical research on rare disorders like Banti’s Syndrome.
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